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HEPARIN COFACTOR II
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DeCS
Descriptor
English
:
Heparin Cofactor II
Descriptor
Spanish
:
Cofactor II de Heparina
Descriptor
Portuguese
:
Cofator II da Heparina
Synonyms
English
:
Heparin Co-Factor II
Heparin Cofactor 2
Leuserpin 2
Protease Inhibitor Leuserpin 2
Serpin D1
Heparin Co Factor II
Tree Number:
D12.644.861.060.750
D12.776.124.790.106.450
D12.776.377.715.085.450
D12.776.872.060.750
Definition
English
:
A sulfated
plasma
protein with a MW of approximately 66kDa that resembles
ANTITHROMBIN III
. The protein is an inhibitor of
thrombin
in
plasma
and is activated by
dermatan sulfate
or
heparin
. It is a member of the serpin superfamily.
Pharmacological Action:
Antithrombins
Serine Proteinase Inhibitors
History Note
English
:
90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
24709
Unique Identifier:
D015844
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS